Thursday, November 21, 2013

Bird Flu: Human Infection


Bird flu is a disease caused by a specific type of hen (bird) influenza virus, a particular so-called H5N1 virus. This virus was first discovered your own body birds in China durring an 1997, and since thus has infected 125 us a in Vietnam, Cambodia, Thailand, moreover Indonesia, killing 64 of them. It is spread through infected migratory birds (including relaxed ducks and geese) to check out domestic poultry (primarily hens, ducks, and turkeys), also to humans.

Some infected all of us have developed abnormal clotting profiles contributing to excessive bleeding— which was a frequent clinical symptom in the way deadly so-called Spanish flu virus of 1918-19, which killed more than 100 million people many countries. Indeed, bird flu shares a number of disturbing characteristics with the actual precise 1918-19 influenza virus. These two viruses have, in truth, recently been shown to be similar genetically. And during a recent laboratory experiment on this mice, the 1918-19 virus was found to produce 39, 000 fold viruses four days after infection compared to the regular seasonal human virus strain. The 1918-19 virus killed 100 percent of the mice which were infected with it, compared to none of the mice infected with the normal flu strain. With a current “ case fatality percentage, ” or death interest rate approximately 50 percent your own body humans, bird flu is obviously also a very deadly disease.

There are don't assume all reports in the the medical field literature describing the clinical interesting facts about bird flu in men and women. The clinical spectrum of money H5N1 infection ranges rrn the asymptomatic infection— where she or he doesn’ t even know he or she is infected— to fatal pneumonia combined with multiple organ failure. A lttle bit infected individuals develop filtering system or kidney dysfunction, and there were two children who died during the virus that came to medical assistance because of diarrhea and seizures focused on encephalitis (infection of whenever brain). However, the most common presentation is easily the most fever, cough, and burdens breathing. Approximately 70 percent of patients also have diarrhea, and a few patients have had only gastrointestinal symptoms (such as digestive problems, vomiting, and diarrhea) and no breathing problems.

Deaths have generally been in normally healthy people. The first report in the emergency room literature of deaths for bird flu was on 12 patients living in Hong Kong. Their median age was nine become older, with a range of one to 60 years. All presented with fever, and eight had symptoms or symptoms of upper-respiratory infections (five you need clinical and X-ray evidence of pneumonia when first diagnosed). Gastrointestinal (GI) symptoms, including abdominal pain, vomiting, and diarrhea, were present in 8 patients. There were a full of five deaths (one became with Reye’ s disease, which is associated on this taking aspirin in children).

In a study of 10 patients inside Vietnam with laboratory-confirmed bird influenza (H5N1), the mean age of the patients was 13. 7 years. For eight of having a patients, there was a definite history of either one on one handling of poultry (chickens or ducks) or contact with sick poultry in the week prior to the onset of illness. All can be found in January 2004 with cough, shortness of breath, moreover fever, and seven experienced diarrhea; none had myalgia (muscle aches)— which is often found in the continuous seasonal flu. Notably, oseltamivir (Tamiflu) was administered to five potential customers, four of whom died (treatment may have been started too late longer medication to be effective— it ought to be given within 48 hours after onset of symptoms to be effective). In total, eight of the people died, for an 80 percent case mortality or death rate.

As is clear from the descriptions exceeding, the presenting symptoms of individuals with bird flu are just like the symptoms of the clothing seasonal flu. Infections caused by either the bird-flu virus (H5N1) or perhaps the seasonal influenza virus is only completely asymptomatic— that and is particularly, cause no symptoms at all. Fever, cough, malaise (feeling ill), and gastrointestinal symptoms are common to both infections. Excessive bleeding occurs only with bird flu, but at the present time this symptom doesn’ t appear to be common. Difficulty breathing is a lot more common with severe instances of bird flu, not seasonal flu. Runny nose and sneezing are found only with colds (or allergies).

The cough in either type of infection is exactly what is referred to with regard to your medicine as “ nonproductive” — meaning there is no sputum brought up a tale a minute coughing, or if any sputum is brought up, it is white up and down color. This type of cough is symptom of upper respiratory viral microbe infections. As either type a part of infection progresses or worsens, tissues may be problems, disrupting the normal structure and purpose of the infected cells. This in turn may allow bacteria being and also cause lack of ability. When this happens following the viral infection, it is referred to as a “ secondary” bacterial infection. When this occurs, the color of over a sputum characteristically turns yellow or green. If this happens, antibiotics are indicated to treat the bacterial infection. (Antibiotics are not indicated in the treatment of viral infections, because these people don’ t work. )

It is secure to assume that inside a bird-flu pandemic, most folks that become infected with the actual precise bird-flu virus will no matter what be asymptomatic— having absolutely no symptoms— or their illness will not be severe enough to require hospitalization. The small percentage who do become seriously ill will have to be hospitalized, and treated with either of the two antiviral agents available, oseltamivir (Tamiflu) or zanamivir (Relenza). A smaller subset of its group will develop life-threatening complications like these acute respiratory distress issue (ARDS), which requires treatment by using mechanical ventilator, a respirator.

Some individuals may develop other health problems such as liver fail, kidney failure, neurological problems— such as seizures, paralysis, psychiatric problems such as delirium or psychosis, or bleeding problems. However, it is reasonable to calculate that most people infected will not die and will not have significant residual strikes, although a small watch will.

Bradford Frank, M. D., M. P. H., M. B. A.

The Frank Group

P. O. Box 138

Lakewood, NY 14750

[http://www.AvoidBirdFlu.com]

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